Bert Sakmann
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Bert Sakmann (German pronunciation: [ˈbɛʁt ˈzakˌman] ⓘ; born 12 June 1942) is a German cell physiologist. He shared the Nobel Prize in Physiology or Medicine with Erwin Neher in 1991 for their work on "the function of single ion channels in cells," and the invention of the patch clamp.[3][4] Bert Sakmann was Professor at Heidelberg University and is an Emeritus Scientific Member of the Max Planck Institute for Medical Research in Heidelberg, Germany. Since 2008 he leads an emeritus research group at the Max Planck Institute of Neurobiology.[3][5][6]
Life and career
[edit]Sakmann was born in Stuttgart, the son of Annemarie (née Schaefer), a physical therapist, and Bertold Sakmann, a theater director.[7] Sakmann enrolled in Volksschule in Lindau, and completed the Wagenburg gymnasium in Stuttgart in 1961. He studied medicine from 1967 onwards in Tübingen, Freiburg, Berlin, Paris and Munich. After completing his medical exams at Ludwig-Maximilians University in Munich, he became a medical assistant in 1968 at Munich University, while also working as a scientific assistant (Wissenschaftlicher Assistent) at Munich's Max-Planck-Institut für Psychiatrie, in the Neurophysiology Department under Otto Detlev Creutzfeldt. In 1971 he moved to University College London, where he worked in the Department of Biophysics under Bernard Katz. In 1974, he completed his medical dissertation, under the title Elektrophysiologie der neuralen Helladaptation in der Katzenretina (Electrophysiology of Neural Light Adaption in the Cat Retina) in the Medical Faculty of Göttingen University.[3]
Afterwards (still in 1974), Sakmann returned to the lab of Otto Creutzfeldt, who had meanwhile moved to the Max Planck Institute for Biophysical Chemistry in Göttingen. Sakmann joined the membrane biology group in 1979.
In 1990 he accepted a position at the Faculty of Natural Science Medicine at Heidelberg University. One year later, he became a full university professor at the Faculty of Biology in Heidelberg.
On 2 June 2009, Peter Gruss, the president of the Max Planck Society, announced that Sakmann would serve as the scientific director of the Max Planck Florida Institute, the organization's biomedical research facility at Florida Atlantic University in Jupiter, Florida.
Sakmann is the founder of the Bert-Sakmann-Stiftung.
Awards and honors
[edit]In 1986, Sakmann and Erwin Neher were awarded the Louisa Gross Horwitz Prize from Columbia University. In 1987, he received the Gottfried Wilhelm Leibniz Prize of the Deutsche Forschungsgemeinschaft, which is the highest honour awarded in German research. In 1991, he received the Ralph W. Gerard Prize in Neuroscience, the Harvey Prize and the Nobel prize for Physiology or Medicine along with Neher, with whom he had worked in Göttingen.[3] In 1993 he became a member of the German Academy of Sciences Leopoldina.[8] He was elected a Foreign Member of the Royal Society (ForMemRS) in 1994.[2]
References
[edit]- ^ "Professor Bert SAKMANN". Jeantet. 1 October 2017.
- ^ a b "Professor Bert Sakmann ForMemRS". London: Royal Society. Archived from the original on 10 October 2015.
- ^ a b c d "Nobel autobiography". Archived from the original on 15 December 2010.
- ^ Hamill, O. P.; Marty, A.; Neher, E.; Sakmann, B.; Sigworth, F. J. (1981). "Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches". Pflügers Archiv: European Journal of Physiology. 391 (2): 85–100. CiteSeerX 10.1.1.456.107. doi:10.1007/BF00656997. PMID 6270629. S2CID 12014433.
- ^ Betz, W.; Sakmann, B. (1971). ""Disjunction" of frog neuromuscular synapses by treatment with proteolytic enzymes". Nature New Biology. 232 (29): 94–95. doi:10.1038/newbio232094a0. hdl:21.11116/0000-0001-3090-5. PMID 4328253.
- ^ Betz, W.; Sakmann, B. (1973). "Effects of proteolytic enzymes on function and structure of frog neuromuscular junctions". The Journal of Physiology. 230 (3): 673–688. doi:10.1113/jphysiol.1973.sp010211. PMC 1350622. PMID 4352108.
- ^ "Bert Sakmann – Biographical, The Nobel Prize in Physiology or Medicine 1991". NobelPrize.org. Nobel Media AB. Retrieved 15 December 2019.
- ^ "Bert Sakmann". German Academy of Sciences Leopoldina. Retrieved 1 June 2021.
External links
[edit]- Bert Sakmann on Nobelprize.org
- 1942 births
- Living people
- Alumni of University College London
- Members of the European Molecular Biology Organization
- Foreign members of the Royal Society
- Humboldt University of Berlin alumni
- 21st-century German biologists
- German Nobel laureates
- Gottfried Wilhelm Leibniz Prize winners
- Foreign associates of the National Academy of Sciences
- Nobel laureates in Physiology or Medicine
- Scientists from Stuttgart
- Recipients of the Pour le Mérite (civil class)
- Recipients of the Order of Merit of Baden-Württemberg
- University of Freiburg alumni
- Academic staff of Heidelberg University
- Ludwig Maximilian University of Munich alumni
- Max Planck Society people
- Electrophysiologists
- Members of the German National Academy of Sciences Leopoldina
- 20th-century German biologists
- Members of the Göttingen Academy of Sciences and Humanities
- Max Planck Institute directors